Soundcard start-up latency is the time it takes from telling the computer to play a sound to when the sound actually comes out of the speakers or headphones.
Professional musicians have to deal with such issues regularly and a lag over a few milliseconds is considered unacceptable to the trained human ear. Empirical tests have shown that soundcards used in typical psychology studies can have start-up latencies in the hundreds of milliseconds. This can make presentation timing and synchronisation with other equipment a real issue.
For example, Psychology Software Tools (PST) the authors of E-Prime have conducted tests where start-up latencies were anywhere between a few milliseconds to over 350 milliseconds. This is in no way the fault of E-Prime but rather the hardware and operating systems used.
To compound the problem newer operating systems are actually worse than older ones. In the PST tests Windows XP did not have any soundcards with a start-up latency over 20 milliseconds. Windows Vista was averaged over 50 milliseconds and Windows 7 well into the 100's of milliseconds of lag. An excerpt from PST's results is shown below to illustrate the startling range of variation.
Adapter
Type
Machine
Operating System
Driver
API/Expected Latency
Mean (ms)
StdDev
Min (ms)
Max (ms)
Sound Blaster SB0880 X-Fi
PCIe
Ad Hoc Quad Core
Win 7x64
manufacturer
DirectSound
344.267
830.216
119.000
3345.000
Asus Xonar DG
PCI
Ad Hoc Quad Core
Win 7x64
manufacturer
DirectSound
69.643
1.277
68.000
72.000
Excerpt from PST's research on soundcard start-up latency